package com.ipsen.medical.entity;

import javax.persistence.*;
import lombok.Data;
import java.time.LocalDateTime;

/**
 * 临床试验实体
 */
@Data
@Entity
@Table(name = "clinical_trials", 
       uniqueConstraints = @UniqueConstraint(columnNames = {"inquiry_id", "nct_id"}))
public class ClinicalTrial {
    
    @Id
    @GeneratedValue(strategy = GenerationType.IDENTITY)
    private Long id;
    
    @Column(name = "inquiry_id")
    private Long inquiryId; // 关联的查询请求ID
    
    @Column(name = "nct_id")
    private String nctId; // NCT编号（ClinicalTrials.gov的唯一标识）
    
    @Column(name = "study_title", columnDefinition = "TEXT")
    private String studyTitle; // 研究标题
    
    @Column(name = "brief_title")
    private String briefTitle; // 简短标题
    
    @Column(name = "official_title", columnDefinition = "TEXT")
    private String officialTitle; // 官方标题
    
    @Column(name = "overall_status")
    private String overallStatus; // 研究状态
    
    @Column(name = "start_date")
    private String startDate; // 开始日期
    
    @Column(name = "completion_date")
    private String completionDate; // 完成日期
    
    @Column(name = "study_type")
    private String studyType; // 研究类型
    
    @Column(name = "phase")
    private String phase; // 研究阶段
    
    @Column(name = "enrollment")
    private Integer enrollment; // 入组人数
    
    @Column(name = "conditions", columnDefinition = "TEXT")
    private String conditions; // 适应症（JSON数组）
    
    @Column(name = "interventions", columnDefinition = "TEXT")
    private String interventions; // 干预措施（JSON数组）
    
    @Column(name = "sponsor")
    private String sponsor; // 主要研究者/机构
    
    @Column(name = "collaborators", columnDefinition = "TEXT")
    private String collaborators; // 合作者（JSON数组）
    
    @Column(name = "locations", columnDefinition = "TEXT")
    private String locations; // 研究地点（JSON数组）
    
    @Column(name = "brief_summary", columnDefinition = "TEXT")
    private String briefSummary; // 简要摘要
    
    @Column(name = "detailed_description", columnDefinition = "TEXT")
    private String detailedDescription; // 详细描述
    
    @Column(name = "primary_outcome", columnDefinition = "TEXT")
    private String primaryOutcome; // 主要终点
    
    @Column(name = "secondary_outcome", columnDefinition = "TEXT")
    private String secondaryOutcome; // 次要终点
    
    @Column(name = "eligibility_criteria", columnDefinition = "TEXT")
    private String eligibilityCriteria; // 入选标准
    
    @Column(name = "url")
    private String url; // ClinicalTrials.gov链接
    
    @Column(name = "raw_data", columnDefinition = "LONGTEXT")
    private String rawData; // 原始API返回数据（JSON格式）
    
    @Column(name = "created_at", nullable = false)
    private LocalDateTime createdAt;
    
    @Column(name = "updated_at")
    private LocalDateTime updatedAt;
    
    @PrePersist
    protected void onCreate() {
        createdAt = LocalDateTime.now();
    }
    
    @PreUpdate
    protected void onUpdate() {
        updatedAt = LocalDateTime.now();
    }
}