213 lines
8.8 KiB
SQL
213 lines
8.8 KiB
SQL
-- 医学信息支持系统数据库初始化脚本
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-- Database: medical_info_system
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CREATE DATABASE IF NOT EXISTS medical_info_system
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DEFAULT CHARACTER SET utf8mb4
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DEFAULT COLLATE utf8mb4_unicode_ci;
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USE medical_info_system;
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-- 用户表
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CREATE TABLE IF NOT EXISTS users (
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id BIGINT PRIMARY KEY AUTO_INCREMENT,
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username VARCHAR(50) NOT NULL UNIQUE,
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password VARCHAR(255) NOT NULL,
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full_name VARCHAR(100) NOT NULL,
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email VARCHAR(100),
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role VARCHAR(20) NOT NULL COMMENT 'ADMIN, MEDICAL_SPECIALIST, REVIEWER',
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enabled BOOLEAN DEFAULT TRUE,
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created_at DATETIME NOT NULL,
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last_login_at DATETIME,
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INDEX idx_username (username),
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INDEX idx_role (role)
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) ENGINE=InnoDB DEFAULT CHARSET=utf8mb4 COLLATE=utf8mb4_unicode_ci;
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-- 查询请求表
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CREATE TABLE IF NOT EXISTS inquiry_requests (
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id BIGINT PRIMARY KEY AUTO_INCREMENT,
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request_number VARCHAR(50) NOT NULL UNIQUE,
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customer_name VARCHAR(100) NOT NULL,
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customer_email VARCHAR(100),
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customer_title VARCHAR(100),
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inquiry_content TEXT,
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keywords TEXT COMMENT '提取的关键词（JSON格式）',
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status VARCHAR(20) NOT NULL COMMENT 'PENDING, KEYWORD_EXTRACTED, SEARCHING, SEARCH_COMPLETED, UNDER_REVIEW, DOWNLOADING, COMPLETED, REJECTED',
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search_results TEXT COMMENT '检索结果（JSON格式）',
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response_content TEXT COMMENT '回复内容',
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assigned_to VARCHAR(50),
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created_at DATETIME NOT NULL,
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updated_at DATETIME,
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completed_at DATETIME,
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INDEX idx_request_number (request_number),
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INDEX idx_status (status),
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INDEX idx_customer_name (customer_name),
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INDEX idx_assigned_to (assigned_to),
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INDEX idx_created_at (created_at)
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) ENGINE=InnoDB DEFAULT CHARSET=utf8mb4 COLLATE=utf8mb4_unicode_ci;
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-- 知识库表
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CREATE TABLE IF NOT EXISTS knowledge_bases (
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id BIGINT PRIMARY KEY AUTO_INCREMENT,
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name VARCHAR(100) NOT NULL,
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type VARCHAR(20) NOT NULL COMMENT 'INTERNAL, PUBLIC, EXTENDED',
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description TEXT,
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data_source VARCHAR(255),
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priority INT COMMENT '检索优先级（数字越小优先级越高）',
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enabled BOOLEAN DEFAULT TRUE,
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configuration TEXT COMMENT '配置信息（JSON格式）',
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created_at DATETIME NOT NULL,
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updated_at DATETIME,
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INDEX idx_type (type),
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INDEX idx_enabled (enabled),
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INDEX idx_priority (priority)
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) ENGINE=InnoDB DEFAULT CHARSET=utf8mb4 COLLATE=utf8mb4_unicode_ci;
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-- 文献表
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CREATE TABLE IF NOT EXISTS literatures (
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id BIGINT PRIMARY KEY AUTO_INCREMENT,
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inquiry_request_id BIGINT,
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title VARCHAR(500) NOT NULL,
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authors VARCHAR(500),
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journal VARCHAR(200),
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publication_date VARCHAR(50),
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doi VARCHAR(100),
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pmid VARCHAR(50),
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abstract_text TEXT,
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source_database VARCHAR(50),
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source_url VARCHAR(500),
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file_path VARCHAR(500),
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download_status VARCHAR(20) COMMENT 'PENDING, DOWNLOADING, COMPLETED, FAILED',
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selected BOOLEAN DEFAULT FALSE,
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created_at DATETIME NOT NULL,
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downloaded_at DATETIME,
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INDEX idx_inquiry_request_id (inquiry_request_id),
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INDEX idx_download_status (download_status),
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INDEX idx_selected (selected),
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FOREIGN KEY (inquiry_request_id) REFERENCES inquiry_requests(id) ON DELETE CASCADE
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) ENGINE=InnoDB DEFAULT CHARSET=utf8mb4 COLLATE=utf8mb4_unicode_ci;
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-- 审核日志表
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CREATE TABLE IF NOT EXISTS audit_logs (
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id BIGINT PRIMARY KEY AUTO_INCREMENT,
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inquiry_request_id BIGINT,
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user_id BIGINT,
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action VARCHAR(20) NOT NULL COMMENT 'SUBMITTED, APPROVED, REJECTED, REVISION_REQUESTED, COMPLETED',
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comments TEXT,
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created_at DATETIME NOT NULL,
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INDEX idx_inquiry_request_id (inquiry_request_id),
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INDEX idx_user_id (user_id),
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INDEX idx_created_at (created_at),
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FOREIGN KEY (inquiry_request_id) REFERENCES inquiry_requests(id) ON DELETE CASCADE,
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FOREIGN KEY (user_id) REFERENCES users(id) ON DELETE SET NULL
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) ENGINE=InnoDB DEFAULT CHARSET=utf8mb4 COLLATE=utf8mb4_unicode_ci;
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-- 药物表
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CREATE TABLE IF NOT EXISTS drugs (
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id BIGINT PRIMARY KEY AUTO_INCREMENT,
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drug_code VARCHAR(50) NOT NULL UNIQUE,
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generic_name VARCHAR(200) NOT NULL,
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trade_name VARCHAR(200),
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active_ingredient VARCHAR(200),
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description TEXT,
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manufacturer VARCHAR(200),
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approval_number VARCHAR(100),
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indications TEXT,
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dosage_and_administration TEXT,
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contraindications TEXT,
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therapeutic_class VARCHAR(100),
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atc_code VARCHAR(20),
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status VARCHAR(20) NOT NULL DEFAULT 'ACTIVE' COMMENT 'ACTIVE, SUSPENDED, WITHDRAWN',
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created_at DATETIME NOT NULL,
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updated_at DATETIME,
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INDEX idx_drug_code (drug_code),
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INDEX idx_generic_name (generic_name),
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INDEX idx_trade_name (trade_name),
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INDEX idx_therapeutic_class (therapeutic_class),
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INDEX idx_status (status)
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) ENGINE=InnoDB DEFAULT CHARSET=utf8mb4 COLLATE=utf8mb4_unicode_ci;
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-- 药物安全信息表
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CREATE TABLE IF NOT EXISTS drug_safety_infos (
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id BIGINT PRIMARY KEY AUTO_INCREMENT,
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drug_id BIGINT NOT NULL,
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source VARCHAR(30) NOT NULL COMMENT 'INTERNAL, LITERATURE, REGULATORY, SOCIAL_MEDIA, CLINICAL_TRIAL',
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title VARCHAR(500) NOT NULL,
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content TEXT,
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category VARCHAR(50) NOT NULL COMMENT 'ADVERSE_REACTION, DRUG_INTERACTION, CONTRAINDICATION, etc.',
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severity_level VARCHAR(20) COMMENT 'MILD, MODERATE, SEVERE, CRITICAL',
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reference_url VARCHAR(500),
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reference_document VARCHAR(500),
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reported_by VARCHAR(100),
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reported_at DATETIME,
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additional_info TEXT COMMENT 'JSON格式的附加信息',
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verified BOOLEAN DEFAULT FALSE,
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verified_by VARCHAR(100),
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verified_at DATETIME,
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created_at DATETIME NOT NULL,
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updated_at DATETIME,
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INDEX idx_drug_id (drug_id),
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INDEX idx_source (source),
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INDEX idx_category (category),
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INDEX idx_severity_level (severity_level),
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INDEX idx_verified (verified),
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FOREIGN KEY (drug_id) REFERENCES drugs(id) ON DELETE CASCADE
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) ENGINE=InnoDB DEFAULT CHARSET=utf8mb4 COLLATE=utf8mb4_unicode_ci;
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-- 临床试验表
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CREATE TABLE IF NOT EXISTS clinical_trials (
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id BIGINT PRIMARY KEY AUTO_INCREMENT,
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inquiry_id BIGINT COMMENT '关联的查询请求ID',
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nct_id VARCHAR(50) NOT NULL COMMENT 'ClinicalTrials.gov唯一标识',
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study_title TEXT COMMENT '研究标题',
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brief_title VARCHAR(500) COMMENT '简短标题',
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official_title TEXT COMMENT '官方标题',
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overall_status VARCHAR(50) COMMENT '研究状态',
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start_date VARCHAR(50) COMMENT '开始日期',
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completion_date VARCHAR(50) COMMENT '完成日期',
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study_type VARCHAR(50) COMMENT '研究类型',
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phase VARCHAR(50) COMMENT '研究阶段',
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enrollment INT COMMENT '入组人数',
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conditions TEXT COMMENT '适应症（JSON数组）',
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interventions TEXT COMMENT '干预措施（JSON数组）',
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sponsor VARCHAR(500) COMMENT '主要研究者/机构',
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collaborators TEXT COMMENT '合作者（JSON数组）',
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locations TEXT COMMENT '研究地点（JSON数组）',
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brief_summary TEXT COMMENT '简要摘要',
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detailed_description LONGTEXT COMMENT '详细描述',
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primary_outcome TEXT COMMENT '主要终点',
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secondary_outcome TEXT COMMENT '次要终点',
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eligibility_criteria TEXT COMMENT '入选标准',
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url VARCHAR(500) COMMENT 'ClinicalTrials.gov链接',
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raw_data LONGTEXT COMMENT '原始API返回数据（JSON格式）',
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created_at DATETIME NOT NULL,
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updated_at DATETIME,
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INDEX idx_inquiry_id (inquiry_id),
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INDEX idx_nct_id (nct_id),
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INDEX idx_overall_status (overall_status),
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INDEX idx_phase (phase),
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INDEX idx_created_at (created_at),
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UNIQUE KEY uk_inquiry_nct (inquiry_id, nct_id),
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FOREIGN KEY (inquiry_id) REFERENCES inquiry_requests(id) ON DELETE CASCADE
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) ENGINE=InnoDB DEFAULT CHARSET=utf8mb4 COLLATE=utf8mb4_unicode_ci;
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-- 插入默认管理员用户 (密码: admin123, 实际使用时应该加密)
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INSERT INTO users (username, password, full_name, email, role, enabled, created_at)
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VALUES ('admin', '$2a$10$rK8WpQYJzxJ8Y5X5YqFvRO5K7K5K7K5K7K5K7K5K7K5K7K5K7K5K7',
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'系统管理员', 'admin@ipsen.com', 'ADMIN', TRUE, NOW())
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ON DUPLICATE KEY UPDATE username=username;
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-- 插入示例知识库配置
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INSERT INTO knowledge_bases (name, type, description, data_source, priority, enabled, created_at)
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VALUES
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('企业研究数据库', 'INTERNAL', '益普生内部研究数据和历史回复', 'internal_db', 1, TRUE, NOW()),
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('PubMed', 'PUBLIC', '美国国家医学图书馆公开数据库', 'https://pubmed.ncbi.nlm.nih.gov', 2, TRUE, NOW()),
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('EMBASE', 'PUBLIC', 'Elsevier医学文献数据库', 'https://www.embase.com', 3, TRUE, NOW()),
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('中国知网', 'PUBLIC', '中国学术期刊数据库', 'https://www.cnki.net', 4, TRUE, NOW()),
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('ClinicalTrials.gov', 'PUBLIC', '临床试验注册数据库', 'https://clinicaltrials.gov', 5, TRUE, NOW()),
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('疾病药物关联库', 'EXTENDED', '疾病与药物关联扩展数据', 'extended_db', 6, TRUE, NOW())
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ON DUPLICATE KEY UPDATE name=name;
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